Amidst the backdrop of America's 2011 recession and the Occupy Wall Street movement, 'Sirens & Muses' follows four young artists at the prestigious Wrynn College of Art. Newcomer Louisa Arceneaux, on a scholarship and seeking her artistic voice, quickly becomes entangled in a web of passion and conflict that challenges the boundaries of art and desire. Her journey is intertwined with that of her enigmatic roommate, Karina Piontek, whose talent and temperament captivate both Louisa and the art community. Their complex relationship evolves against the rising tension between a provocative anti-capitalist student and a politically-minded visiting professor. As ideals clash and a scandalous hoax rocks their insulated world, the characters are propelled into New York's ruthless art landscape, driving each to question identity, love, and what it means to create in an era of tumultuous change.