In a world where medical breakthroughs promise the gift of prolonged youth, geneticist Dr. Henry Moss stands at a crossroads between ethics and ambition. His research into a disease causing premature aging in children morphs into a potential fountain of youth when a young patient's sibling exhibits signs of immoral but miraculous halted aging. In the tech-fueled atmosphere of dot-com Seattle, Henry's own family's desires and struggles mirror his quandary. His wife, underutilized in her profession, and their teenage children, wrestling with their own dreams and mistakes, create a mosaic of moral dilemmas and personal reckonings. 'Long for This World' is both a delicate family saga and a probing look into the ramifications of defying nature's course.