At its core, 'We Are All Completely Beside Ourselves' narrates the complex tale of Rosemary Cooke as she grapples with the repercussions of her unique childhood. Rosemary's memories revolve around Fern, the chimpanzee who was raised as her sister, and the profound silence that filled her life after Fern's departure. With the narrative starting in the middle of the story and journeying back and forth, Fowler constructs a poignant exploration of family bonds, lost siblings, and painful secrets. The story delves into ethical dimensions of science and what it means to be human, all seen through Rosemary's tender and introspective voice.