Ruth Emeraldine, haunted by her brother's suicide post-WWI, dedicates herself to the aid of the mentally ill, aligning her dreams with the meteoric rise of a groundbreaking treatment: the lobotomy. Her belief is intertwined with her love for its herald, the mesmerizing Dr. Robert Apter. Yet as Robert's methods become increasingly reckless, Ruth's hope teeters on the brink of despair. Margaret Baxter, a young mother crushed under the weight of her 'baby blues' is recommended the procedure by Dr. Apter, believing it as her salvation. But when Ruth witnesses the dire fallout of her husband's practice, a chilling reality unfolds, and she must fight to save Margaret and others from the grim consequences of a misguided genius. 'The Lobotomist's Wife' peers into the shadows of a haunting medical era, charting one woman's courageous stand against the darkness.